

| Catalog No. | HC876012 |
|---|---|
| Description |
Recombinant Human TIMM23 Protein, N-GST & C-His (HC876012) expressed in E. coli, spanning Glu2-Arg72. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | O14925 |
| Protein length | Glu2-Arg72 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 35.32 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | Mitochondrial import inner membrane translocase subunit Tim23, TIM23, TIMM23 |
| Background | Mitochondrial import inner membrane translocase subunit Tim23 is a ~21 kDa protein. Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has a role in the activation of stress-induced mitophagy by protecting PINK1 from OMA1-mediated degradation and facilitating its accumulation at the outer mitochondrial membrane in response to depolarization. 1. Bauer, MF. et al. (1999) Journal of molecular biology 289, 69-82. PMID: 10339406 2. Akabane, S. et al. (2023) Cell reports 42, 112454. PMID: 37160114 |
| Note | For research use only |
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