Human TK2 Recombinant Protein (N-His) (HC856012)

Name: Human TK2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC856012
Price: 211 USD
Availability: InStock

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Catalog No.	HC856012
Description	Recombinant Human TK2 Protein, N-His (HC856012) expressed in E. coli, spanning Ser51-Pro265. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	O00142
Protein length	Ser51-Pro265
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	27.65 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2'-deoxyuridine kinase TK2, Deoxycytidine kinase TK2, EC:2.7.1.-, EC:2.7.1.21, EC:2.7.1.74, Mt-TK, TK2, Thymidine kinase 2, mitochondrial
Background	Thymidine kinase 2, mitochondrial is a ~31 kDa protein. Phosphorylates thymidine, deoxycytidine, and deoxyuridine in the mitochondrial matrix. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on TK2 and DGUOK. Widely used as target of antiviral and chemotherapeutic agents. 1. Saada, A. et al. (2001) Nature genetics 29, 342-4. PMID: 11687801 2. Wang, L. et al. (1999) FEBS letters 443, 170-4. PMID: 9989599
Note	For research use only

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Datasheet

Human TK2 Recombinant Protein (N-His).pdf

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Human TK2 Recombinant Protein (N-His) (HC856012)

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