Human TMEM106B Recombinant Protein (N-His) (HA136012)

Name: Human TMEM106B Recombinant Protein (N-His)
Brand: abinScience
SKU: HA136012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HA136012
Description	Recombinant Human TMEM106B Protein, N-His (HA136012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q9NUM4
Protein length	Pro118-Gln274
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	TMEM106B, Transmembrane protein 106B
Background	Transmembrane protein 106B is a ~31 kDa protein. In neurons, involved in the transport of late endosomes/lysosomes. May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking. May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6. In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment. It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is important in the sorting of lysosomes in axons or in dendrites. 1. Stagi, M. et al. (2014) Molecular and cellular neurosciences 61, 226-40. PMID: 25066864
Note	For research use only

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Datasheet

Human TMEM106B Recombinant Protein (N-His).pdf

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Human TMEM106B Recombinant Protein (N-His) (HA136012)

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