Human TP53BP2 Recombinant Protein (N-His) (HD860012)

Name: Human TP53BP2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD860012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD860012
Description	Recombinant Human TP53BP2 Protein, N-His (HD860012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q13625
Protein length	Val922-Ala1128
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	53BP2, ASPP2, Apoptosis-stimulating of p53 protein 2, BBP, Bbp, Bcl2-binding protein, Renal carcinoma antigen NY-REN-51, TP53BP2, Tumor suppressor p53-binding protein 2, p53-binding protein 2, p53BP2
Background	Apoptosis-stimulating of p53 protein 2 is a ~125 kDa protein. Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions with proteins such as TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of NAE1 to conjugate NEDD8 to CUL1, and thereby decreases NAE1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. 1. Bergamaschi, D. et al. (2003) Nature genetics 33, 162-7. PMID: 12524540
Note	For research use only

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Datasheet

Human TP53BP2 Recombinant Protein (N-His).pdf

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Human TP53BP2 Recombinant Protein (N-His) (HD860012)

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