

| Catalog No. | HC890012 |
|---|---|
| Description |
Recombinant Human TP73 Protein, N-His (HC890012) expressed in E. coli, spanning His125-Ala324. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | O15350 |
| Protein length | His125-Ala324 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 24.60 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | P73, TP73, Tumor protein p73, p53-like transcription factor, p53-related protein |
| Background | Tumor protein p73 is a ~69 kDa protein. Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. Is an activator of FOXJ1 expression. It is an essential factor for the positive regulation of lung ciliated cell differentiation. 1. Wallmeier, J. et al. (2021) American journal of human genetics 108, 1318-1329. PMID: 34077761 |
| Note | For research use only |
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