Human TRAF7 Recombinant Protein (N-His) (HD350012)

Name: Human TRAF7 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD350012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD350012
Description	Recombinant Human TRAF7 Protein, N-His (HD350012) expressed in E. coli, spanning Ile385-Cys670. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q6Q0C0
Protein length	Ile385-Cys670
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	33.95 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	E3 ubiquitin-protein ligase TRAF7, EC:2.3.2.-, EC:2.3.2.27, RFWD1, RING finger and WD repeat-containing protein 1, RING finger protein 119, RING-type E3 ubiquitin transferase TRAF7, RNF119, TNF receptor-associated factor 7, TRAF7
Background	E3 ubiquitin-protein ligase TRAF7 is a ~74 kDa protein. E3 ubiquitin and SUMO-protein ligase that plays a role in different biological processes such as innate immunity, inflammation or apoptosis. Potentiates MAP3K3-mediated activation of JUN/AP1 and DDIT3 transcriptional regulators. Negatively regulates MYB transcriptional activity by sequestering it to the cytosol via SUMOylation. Plays a role in the phosphorylation of MAPK1 and/or MAPK3, probably via its interaction with MAP3K3. Negatively regulates RLR-mediated innate immunity by promoting 'Lys-48'-linked ubiquitination of TBK1 through its RING domain to inhibit the cellular antiviral response. 1. Xu, LG. et al. (2004) The Journal of biological chemistry 279, 17278-82. PMID: 15001576 2. Huang, JP. et al. (2023) Virologica Sinica 38, 419-428. PMID: 37086853 3. Bouwmeester, T. et al. (2004) Nature cell biology 6, 97-105. PMID: 14743216 4. Zotti, T. et al. (2011) The Journal of biological chemistry 286, 22924-33. PMID: 21518757
Note	For research use only

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SDS-PAGE for Human TRAF7 Recombinant Protein (N-His)

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Datasheet

Human TRAF7 Recombinant Protein (N-His).pdf

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Human TRAF7 Recombinant Protein (N-His) (HD350012)

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