Human UBA6 Recombinant Protein (N-His) (HC826012)

Name: Human UBA6 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC826012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC826012
Description	Recombinant Human UBA6 Protein, N-His (HC826012) expressed in E. coli, spanning Pro623-Gly888. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	A0AVT1
Protein length	Pro623-Gly888
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	32.87 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	E1-L2, EC:6.2.1.45, MOP-4, MOP4, Monocyte protein 4, UBA6, UBE1L2, Ubiquitin-activating enzyme 6, Ubiquitin-activating enzyme E1-like protein 2, Ubiquitin-like modifier-activating enzyme 6
Background	Ubiquitin-like modifier-activating enzyme 6 is a ~117 kDa protein. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Also activates UBD/FAT10 conjugation via adenylation of its C-terminal glycine. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. 1. Truongvan, N. et al. (2022) Nature communications 13, 4789. PMID: 35970836 2. Yuan, L. et al. (2022) Nature communications 13, 4880. PMID: 35986001 3. Chiu, YH. et al. (2007) Molecular cell 27, 1014-23. PMID: 17889673
Note	For research use only

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Human UBA6 Recombinant Protein (N-His).pdf

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Human UBA6 Recombinant Protein (N-His) (HC826012)

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