Human UBE2V1 Recombinant Protein (N-His) (HD197012)

Name: Human UBE2V1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD197012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD197012
Description	Recombinant Human UBE2V1 Protein, N-His (HD197012) expressed in E. coli, spanning Met1-Asn147. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q13404
Protein length	Met1-Asn147
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	18.66 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CROC-1, CROC1, TRAF6-regulated IKK activator 1 beta Uev1A, UBE2V, UBE2V1, UEV-1, UEV1, Ubiquitin-conjugating enzyme E2 variant 1
Background	Ubiquitin-conjugating enzyme E2 variant 1 is a ~16 kDa protein. Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. 1. Cadena, C. et al. (2019) Cell 177, 1187-1200.e16. PMID: 31006531
Note	For research use only

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Datasheet

Human UBE2V1 Recombinant Protein (N-His).pdf

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Human UBE2V1 Recombinant Protein (N-His) (HD197012)

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