Human USP33 Recombinant Protein (N-His) (HA936022)

Name: Human USP33 Recombinant Protein (N-His)
Brand: abinScience
SKU: HA936022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HA936022
Description	Recombinant Human USP33 Protein, N-His (HA936022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q8TEY7
Protein length	Arg36-Glu120
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Deubiquitinating enzyme 33, EC:3.4.19.12, KIAA1097, USP33, Ubiquitin carboxyl-terminal hydrolase 33, Ubiquitin thioesterase 33, Ubiquitin-specific-processing protease 33, VDU1, VHL-interacting deubiquitinating enzyme 1, hVDU1
Background	Ubiquitin carboxyl-terminal hydrolase 33 is a ~106 kDa protein. Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. Involved in regulation of centrosome duplication by mediating deubiquitination of CCP110 in S and G2/M phase, leading to stabilize CCP110 during the period which centrioles duplicate and elongate. Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling. Plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2 adrenergic receptor (ADRB2).
Note	For research use only

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Datasheet

Human USP33 Recombinant Protein (N-His).pdf

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Human USP33 Recombinant Protein (N-His) (HA936022)

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