Human VSX2 Recombinant Protein (N-His-KSI) (HD082012)

Name: Human VSX2 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD082012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD082012
Description	Recombinant Human VSX2 Protein, N-His-KSI (HD082012) expressed in E. coli, spanning Thr2-Ala361. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P58304
Protein length	Thr2-Ala361
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	55.04 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CHX10, Ceh-10 homeodomain-containing homolog, HOX10, Homeobox protein CHX10, VSX2, Visual system homeobox 2
Background	Visual system homeobox 2 is a ~39 kDa protein. Acts as a transcriptional regulator through binding to DNA at the consensus sequence 5'-[TC]TAATT[AG][AG]-3' upstream of gene promoters. Plays a significant role in the specification and morphogenesis of the sensory retina. May play a role in specification of V2a interneurons during spinal cord development. Mediates differentiation of V2a interneurons by repression of motor neuron gene transcription, via competitively binding to response elements that are activated by the ISL1-LHX3 complex, such as VSX1. Acts as a positive transcriptional regulator of NXNL1; regulation is significantly increased in synergy with VSX1. 1. Capowski, EE. et al. (2016) Stem cells (Dayton, Ohio) 34, 2625-2634. PMID: 27301076 2. Clark, AM. et al. (2008) Brain research 1192, 99-113. PMID: 17919464 3. Clovis, YM. et al. (2016) Cell reports 16, 1642-1652. PMID: 27477290 4. Dorval, KM. et al. (2006) The Journal of biological chemistry 281, 744-51. PMID: 16236706
Note	For research use only

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Datasheet

Human VSX2 Recombinant Protein (N-His-KSI).pdf

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Human VSX2 Recombinant Protein (N-His-KSI) (HD082012)

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