Human XBP1 Recombinant Protein (N-His-SUMO & C-Strep) (HC167012)

Name: Human XBP1 Recombinant Protein (N-His-SUMO & C-Strep)
Brand: abinScience
SKU: HC167012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC167012
Description	Recombinant Human XBP1 Protein, N-His-SUMO & C-Strep (HC167012) expressed in E. coli, spanning Ser68-Lys151. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P17861
Protein length	Ser68-Lys151
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	23.40 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	TREB-5, TREB5, Tax-responsive element-binding protein 5, X-box-binding protein 1, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1, luminal form, XBP-1, XBP1, XBP2
Background	X-box-binding protein 1 is a ~28 kDa protein. Functions as a transcription factor during endoplasmic reticulum (ER) stress by regulating the unfolded protein response (UPR). Required for cardiac myogenesis and hepatogenesis during embryonic development, and the development of secretory tissues such as exocrine pancreas and salivary gland. Involved in terminal differentiation of B lymphocytes to plasma cells and production of immunoglobulins. Modulates the cellular response to ER stress in a PIK3R-dependent manner. Binds to the cis-acting X box present in the promoter regions of major histocompatibility complex class II genes. 1. Reimold, AM. et al. (2001) Nature 412, 300-7. PMID: 11460154 2. Winnay, JN. et al. (2010) Nature medicine 16, 438-45. PMID: 20348923 3. Ponath, PD. et al. (1993) The Journal of biological chemistry 268, 17074-82. PMID: 8349596
Note	For research use only

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Datasheet

Human XBP1 Recombinant Protein (N-His-SUMO & C-Strep).pdf

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Human XBP1 Recombinant Protein (N-His-SUMO & C-Strep) (HC167012)

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