

| Catalog No. | HC894012 |
|---|---|
| Description |
Recombinant Human YKT6 Protein, N-His (HC894012) expressed in E. coli, spanning Met1-Met198. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | O15498 |
| Protein length | Met1-Met198 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 24.58 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | EC:2.3.1.-, Synaptobrevin homolog YKT6, YKT6 |
| Background | Synaptobrevin homolog YKT6 is a ~22 kDa protein. Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity. Essential for the structural and functional organization of the Golgi apparatus. 1. McNew, JA. et al. (1997) The Journal of biological chemistry 272, 17776-83. PMID: 9211930 2. Tai, G. et al. (2004) Molecular biology of the cell 15, 4011-22. PMID: 15215310 3. Veit, M. (2004) The Biochemical journal 384, 233-7. PMID: 15479160 4. Fukasawa, M. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 4815-20. PMID: 15044687 5. Shirakawa, R. et al. (2020) The EMBO journal 39, e104120. PMID: 32128853 |
| Note | For research use only |
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