Human ZC3H12D Recombinant Protein (N-His) (HP358012)

Name: Human ZC3H12D Recombinant Protein (N-His)
Brand: abinScience
SKU: HP358012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP358012
Description	Recombinant Human ZC3H12D Protein, N-His (HP358012) expressed in E. coli, spanning Arg90-Pro231. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	A2A288
Protein length	Arg90-Pro231
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	19.09 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Probable ribonuclease ZC3H12D, MCP-induced protein 4, Zinc finger CCCH domain-containing protein 12D, TFL, Transformed follicular lymphoma, p34, MCPIP4, ZC3H12D, C6orf95
Background	Probable ribonuclease ZC3H12D is a ~58 kDa protein. May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages. Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation. 1. Minagawa, K. et al. (2009) Molecular cancer research : MCR 7, 880-9. PMID: 19531561 2. Huang, S. et al. (2015) The Journal of biological chemistry 290, 20782-20792. PMID: 26134560 3. Wang, M. et al. (2007) Cancer research 67, 93-9. PMID: 17210687
Note	For research use only.

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SDS-PAGE for Recombinant Human ZC3H12D Protein, N-His

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Datasheet

Human ZC3H12D Recombinant Protein (N-His).pdf

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Formula

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Human ZC3H12D Recombinant Protein (N-His) (HP358012)

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