

| Catalog No. | HD020012 |
|---|---|
| Description |
Recombinant Human ZNF76 Protein, N-His (HD020012) expressed in E. coli, spanning Met1-Glu395. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P36508 |
| Protein length | Met1-Glu395 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 45.91 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | D6S229E, ZNF523, ZNF76, Zinc finger protein 523, Zinc finger protein 76 |
| Background | Zinc finger protein 76 is a ~61 kDa protein. Transcription factor that regulates expression of genes transcribed by both RNA polymerases II and III. Specifically recognizes and binds the Staf-binding site (SBS), a consensus DNA-binding motif present in many promoters. Able to activate expression of small nuclear RNA (snRNA) transcribed by RNA polymerases II and III. Also regulates expression of mRNAs and acts as a DNA-binding transcription repressor that inhibits the activity of the TATA-binding protein (TBP). 1. Kubota, H. et al. (2000) The Journal of biological chemistry 275, 28641-8. PMID: 10893243 2. Myslinski, E. et al. (1998) The Journal of biological chemistry 273, 21998-2006. PMID: 9705341 3. Zheng, G. et al. (2004) The Journal of biological chemistry 279, 42410-21. PMID: 15280358 4. Zheng, G. et al. (2006) Biochemical and biophysical research communications 339, 1069-75. PMID: 16337145 |
| Note | For research use only |
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