Human ZNF93 Recombinant Protein (N-His) (HD019012)

Name: Human ZNF93 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD019012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD019012
Description	Recombinant Human ZNF93 Protein, N-His (HD019012) expressed in E. coli, spanning Phe145-Pro620. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P35789
Protein length	Phe145-Pro620
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	56.68 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ZNF505, ZNF93, Zinc finger protein 505, Zinc finger protein 93, Zinc finger protein HTF34
Background	Zinc finger protein 93 is a ~70 kDa protein. Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1. Not able to repress expression of all subtypes of L1 elements. Binds to the 5' end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs. 50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression. 1. Jacobs, FM. et al. (2014) Nature 516, 242-5. PMID: 25274305
Note	For research use only

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Human ZNF93 Recombinant Protein (N-His).pdf

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Human ZNF93 Recombinant Protein (N-His) (HD019012)

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