Mouse ACVR1B Recombinant Protein (C-Fc) (MW381031)

Name: Mouse ACVR1B Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MW381031
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MW381031
Description	Recombinant Mouse ACVR1B Protein, C-Fc (MW381031) expressed in Mammalian Cells, spanning Leu32-Glu126. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q61271
Protein length	Leu32-Glu126
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	38.91 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ACTR-IB, ACVR1B, ACVRLK4, ALK-4, ALK4, Activin receptor type IB, Activin receptor type-1B, Activin receptor-like kinase 4, EC:2.7.11.30, SKR2, Serine/threonine-protein kinase receptor R2
Background	Activin receptor type-1B is a ~56 kDa protein. Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2 (ACVR2A or ACVR2B). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating a many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, type-2 receptors (ACVR2A and/or ACVR2B) act as a primary activin receptors whereas the type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase.
Note	For research use only

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Datasheet

Mouse ACVR1B Recombinant Protein (C-Fc).pdf

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Mouse ACVR1B Recombinant Protein (C-Fc) (MW381031)

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