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Mouse CCL7/MCP-3 Recombinant Protein (N-GST & C-His) (MX155012)

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Overview
Catalog No.MX155012
Description
Recombinant Mouse CCL7/MCP-3 Protein, N-GST & C-His (MX155012) expressed in E. coli, spanning Lys40-Pro97. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Expression systemE. coli
AccessionQ03366
Protein lengthLys40-Pro97
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesMus musculus (Mouse)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Predicted molecular weight 34.97 kDa
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesC-C motif chemokine 7, CCL7, MCP-3, MCP3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7
Background

C-C motif chemokine 7 is a ~10 kDa protein. Chemotactic factor that plays an important role in immune regulation. Attracts monocytes, eosinophils, basophils, and T-cells to sites of inflammation or infection. Upon binding to various chemokine receptors including CCR1, CCR2, CCR3, and CCR5, facilitates immune cell migration by guiding them to infected tissues. Interacts with CCR2 to facilitate the release of monocytes from the bone marrow into the bloodstream, maintaining monocyte homeostasis. In turn, monocytes recruited to inflamed or injured tissues can differentiate into macrophages or dendritic cells, which are essential for immune defense and tissue repair.

1. Xu, H. et al. (2025) International immunopharmacology 147, 114027. PMID: 39805173
2. Tsou, CL. et al. (2007) The Journal of clinical investigation 117, 902-9. PMID: 17364026
3. Zhu, LP. et al. (2023) Molecular pain 19, 17448069231169373. PMID: 36998150
4. Ford, J. et al. (2018) Frontiers in immunology 9, 3063. PMID: 30671055
Note For research use only
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Formula
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Formula
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