Mouse CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-His) (MV809011)

Name: Mouse CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-His)
Brand: abinScience
SKU: MV809011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MV809011
Description	Recombinant Mouse CD273/PD-L2/PDCD1LG2 Protein, C-His (MV809011) expressed in Mammalian Cells, spanning Leu20-Arg219. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q9WUL5
Protein length	Leu20-Arg219
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	25.44 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	B7-DC, B7DC, Butyrophilin B7-DC, CD273, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, PDL2, Programmed cell death 1 ligand 2, Programmed death ligand 2
Background	Programmed cell death 1 ligand 2 is a ~27 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production. 1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527 2. Tseng, SY. et al. (2001) The Journal of experimental medicine 193, 839-46. PMID: 11283156 3. Wang, S. et al. (2003) The Journal of experimental medicine 197, 1083-91. PMID: 12719480 4. Lázár-Molnár, E. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 10483-8. PMID: 18641123
Note	For research use only

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Datasheet

Mouse CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-His).pdf

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Mouse CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-His) (MV809011)

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