Mouse CRACC/SLAMF7 Recombinant Protein (C-His) (MV217011)

Name: Mouse CRACC/SLAMF7 Recombinant Protein (C-His)
Brand: abinScience
SKU: MV217011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MV217011
Description	Recombinant Mouse CD319/SLAMF7 Protein, C-His (MV217011) expressed in Mammalian Cells, spanning Met1-Gly224. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q8BHK6
Protein length	Met1-Gly224
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	25.64 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CD319, CRACC, CS1, Membrane protein FOAP-12, Novel Ly9, Protein 19A, SLAM family member 7, SLAMF7
Background	SLAM family member 7 is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Mediates natural killer (NK) cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on the adapter SH2D1B. 1. Dong, Z. et al. (2009) Nature immunology 10, 973-80. PMID: 19648922 2. Cruz-Munoz, ME. et al. (2009) Nature immunology 10, 297-305. PMID: 19151721
Note	For research use only

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Datasheet

Mouse CRACC/SLAMF7 Recombinant Protein (C-His).pdf

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Mouse CRACC/SLAMF7 Recombinant Protein (C-His) (MV217011)

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