Mouse CD358/TNFRSF21 Recombinant Protein (C-Fc) (MF685021)

Name: Mouse CD358/TNFRSF21 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MF685021
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MF685021
Description	Recombinant Mouse CD358/TNFRSF21 Protein, C-Fc (MF685021) expressed in Mammalian Cells, spanning Gln42-His349. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q9EPU5
Protein length	Gln42-His349
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	61.91 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CD358, DR6, Death receptor 6, TNFRSF21, Tumor necrosis factor receptor superfamily member 21
Background	Tumor necrosis factor receptor superfamily member 21 is a ~71 kDa protein. Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation. 1. Liu, J. et al. (2001) Immunity 15, 23-34. PMID: 11485735 2. Zhao, H. et al. (2001) The Journal of experimental medicine 194, 1441-8. PMID: 11714751 3. Schmidt, CS. et al. (2003) The Journal of experimental medicine 197, 51-62. PMID: 12515813 4. Mi, S. et al. (2011) Nature medicine 17, 816-21. PMID: 21725297 5. Hu, Y. et al. (2013) Cell death & disease 4, e579. PMID: 23559013
Note	For research use only

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Datasheet

Mouse CD358/TNFRSF21 Recombinant Protein (C-Fc).pdf

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Mouse CD358/TNFRSF21 Recombinant Protein (C-Fc) (MF685021)

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