Mouse CDw293/BMPR1B Recombinant Protein (N-His) (MT371012)

Name: Mouse CDw293/BMPR1B Recombinant Protein (N-His)
Brand: abinScience
SKU: MT371012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MT371012
Description	Recombinant Mouse CDw293/BMPR1B Protein, N-His (MT371012) expressed in E. coli, spanning Lys14-Lys126. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P36898
Protein length	Lys14-Lys126
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	15.01 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BMP type-1B receptor, BMPR-1B, BMPR1B, Bone morphogenetic protein receptor type-1B, CDw293, EC:2.7.11.30
Background	Bone morphogenetic protein receptor type-1B is a ~56 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1. Receptor for GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. 1. Kotzsch, A. et al. (2009) The EMBO journal 28, 937-47. PMID: 19229295 2. Stange, K. et al. (2015) Orphanet journal of rare diseases 10, 84. PMID: 26105076 3. Degenkolbe, E. et al. (2013) PLoS genetics 9, e1003846. PMID: 24098149
Note	For research use only

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Datasheet

Mouse CDw293/BMPR1B Recombinant Protein (N-His).pdf

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Mouse CDw293/BMPR1B Recombinant Protein (N-His) (MT371012)

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