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Mouse CXCL17/DMC/VCC1 Recombinant Protein (N-GST & C-His) (MV053022)

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Overview
Catalog No.MV053022
Description
Recombinant Mouse CXCL17/DMC/VCC1 Protein, N-GST & C-His (MV053022) expressed in E. coli, spanning His36-Leu119. Purity: >90% by SDS-PAGE.
Highlights
  • His-Tagged — N-terminal 6×His tag for IMAC purification.
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% purity verified by SDS-PAGE.
Expression systemE. coli
AccessionQ5UW37
Protein lengthHis36-Leu119
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesMus musculus (Mouse)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Predicted molecular weight 38.04 kDa
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names4-Cys CXCL17, 6-Cys CXCL17, C-X-C motif chemokine 17, CXCL17, DMC, Dendritic cell and monocyte chemokine-like protein, VCC1, VEGF coregulated chemokine 1
Background

C-X-C motif chemokine 17 is a ~13 kDa protein. Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells, and which is involved in immune regulation and lymphocyte trafficking. Activates the C-X-C chemokine receptor GPR25. Plays a key role in lymphocyte homing by activating the receptor GPR25 on lymphocytes, mediating lymphocyte recruitment into the respiratory, upper gastrointestinal, biliary and genito-urinary tracts. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach.

1. Burkhardt, AM. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 1468-74. PMID: 24973458
2. Lowry, E. et al. (2024) Journal of leukocyte biology 115, 1177-1182. PMID: 38298146
3. Weinstein, EJ. et al. (2006) Biochemical and biophysical research communications 350, 74-81. PMID: 16989774
Note For research use only
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Formula
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Formula
C₁ × V₁ = C₂ × V₂
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V₁ (Stock Vol.)
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