

| Catalog No. | MV053022 |
|---|---|
| Description |
Recombinant Mouse CXCL17/DMC/VCC1 Protein, N-GST & C-His (MV053022) expressed in E. coli, spanning His36-Leu119. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q5UW37 |
| Protein length | His36-Leu119 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 38.04 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | 4-Cys CXCL17, 6-Cys CXCL17, C-X-C motif chemokine 17, CXCL17, DMC, Dendritic cell and monocyte chemokine-like protein, VCC1, VEGF coregulated chemokine 1 |
| Background | C-X-C motif chemokine 17 is a ~13 kDa protein. Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells, and which is involved in immune regulation and lymphocyte trafficking. Activates the C-X-C chemokine receptor GPR25. Plays a key role in lymphocyte homing by activating the receptor GPR25 on lymphocytes, mediating lymphocyte recruitment into the respiratory, upper gastrointestinal, biliary and genito-urinary tracts. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. 1. Burkhardt, AM. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 1468-74. PMID: 24973458 2. Lowry, E. et al. (2024) Journal of leukocyte biology 115, 1177-1182. PMID: 38298146 3. Weinstein, EJ. et al. (2006) Biochemical and biophysical research communications 350, 74-81. PMID: 16989774 |
| Note | For research use only |
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