Mouse IL25/IL17E Recombinant Protein (N-His) (MV984012)

Name: Mouse IL25/IL17E Recombinant Protein (N-His)
Brand: abinScience
SKU: MV984012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MV984012
Description	Recombinant Mouse IL25/IL17E Protein, N-His (MV984012) expressed in E. coli, spanning Val17-Ala169. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q8VHH8
Protein length	Val17-Ala169
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	19.75 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IL-17E, IL-25, IL17E, IL25, Interleukin-17E, Interleukin-25
Background	Interleukin-25 is a ~19 kDa protein. Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production. Promotes and augments T-helper type 2 responses locally or systemically. Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction. In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13. Also induces the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways. 1. Fort, MM. et al. (2001) Immunity 15, 985-95. PMID: 11754819 2. Peng, B. et al. (2022) Frontiers in immunology 13, 842500. PMID: 35615348 3. Rickel, EA. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 4299-310. PMID: 18768888
Note	For research use only

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Datasheet

Mouse IL25/IL17E Recombinant Protein (N-His).pdf

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Mouse IL25/IL17E Recombinant Protein (N-His) (MV984012)

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