

| Catalog No. | MD462012 |
|---|---|
| Description |
Recombinant Mouse OR51E2 Protein, N-His (MD462012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q8VBV9 |
| Protein length | Ser2-Gly27&Ser75-Ala98&Lys163-Thr200&Tyr291-Thr320 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 16.14 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | HPRAJ, OR51E2, Olfactory receptor 51E2, Olfactory receptor OR11-16, PSGR, Prostate-specific G-protein coupled receptor |
| Background | Olfactory receptor 51E2 is a ~35 kDa protein. Olfactory receptor. The activity of this receptor is probably mediated by G-proteins which induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1. Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells. Activated by the short chain fatty acids (SCFA), acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure. 1. Pluznick, JL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 4410-5. PMID: 23401498 2. Chang, AJ. et al. (2015) Nature 527, 240-4. PMID: 26560302 3. Torres-Torrelo, H. et al. (2018) Nature 561, E33-E40. PMID: 30258151 |
| Note | For research use only |
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