Mouse RIC8B Recombinant Protein (N-His) (MD465012)

Name: Mouse RIC8B Recombinant Protein (N-His)
Brand: abinScience
SKU: MD465012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MD465012
Description	Recombinant Mouse RIC8B Protein, N-His (MD465012) expressed in E. coli, spanning Met1-Ser291. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q80XE1
Protein length	Met1-Ser291
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	35.39 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Brain synembryn, Chaperone Ric-8B, RIC8B, Synembryn-B, hSyn
Background	Chaperone Ric-8B is a ~58 kDa protein. Chaperone that specifically binds and folds nascent G(s) G-alpha proteins (GNAS and GNAL) prior to G protein heterotrimer formation, promoting their association with the plasma membrane. Also acts as a guanine nucleotide exchange factor (GEF) for G(s) proteins by stimulating exchange of bound GDP for free GTP. Acts as an important component for odorant signal transduction by mediating GNAL (G(olf)-alpha) folding, thereby promoting-dependent cAMP accumulation in olfactory sensory neurons. 1. Gabay, M. et al. (2011) Science signaling 4, ra79. PMID: 22114146 2. Papasergi-Scott, MM. et al. (2023) Structure (London, England : 1993) 31, 553-564.e7. PMID: 36931277 3. Von Dannecker, LE. et al. (2005) The Journal of neuroscience : the official journal of the Society for Neuroscience 25, 3793-800. PMID: 15829631 4. Von Dannecker, LE. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 9310-4. PMID: 16754875 5. Chan, P. et al. (2011) The Journal of biological chemistry 286, 19932-42. PMID: 21467038 6. Machado, CF. et al. (2017) The Journal of neuroscience : the official journal of the Society for Neuroscience 37, 12202-12213. PMID: 29118104
Note	For research use only

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Datasheet

Mouse RIC8B Recombinant Protein (N-His).pdf

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Mouse RIC8B Recombinant Protein (N-His) (MD465012)

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