Mouse S100A4 Recombinant Protein (C-Fc) (MB727011)

Name: Mouse S100A4 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MB727011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MB727011
Description	Recombinant Mouse S100A4 Protein, C-Fc (MB727011) expressed in Mammalian Cells, spanning Ala2-Lys101. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	P07091
Protein length	Ala2-Lys101
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	39.93 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CAPL, Calvasculin, MTS1, Metastasin, Placental calcium-binding protein, Protein Mts1, Protein S100-A4, S100 calcium-binding protein A4, S100A4
Background	Protein S100-A4 is a ~11 kDa protein. Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. 1. Li, ZH. et al. (2010) Molecular biology of the cell 21, 2598-610. PMID: 20519440 2. Kriajevska, MV. et al. (1994) The Journal of biological chemistry 269, 19679-82. PMID: 8051043 3. Grum-Schwensen, B. et al. (2010) Cancer research 70, 936-47. PMID: 20103644
Note	For research use only

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Datasheet

Mouse S100A4 Recombinant Protein (C-Fc).pdf

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Mouse S100A4 Recombinant Protein (C-Fc) (MB727011)

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