

| Catalog No. | MW629012 |
|---|---|
| Description |
Recombinant Mouse SLC1A2 Protein, N-His (MW629012) expressed in E. coli, spanning Tyr493-Lys572. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P43006 |
| Protein length | Tyr493-Lys572 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 11.51 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | EAAT2, Excitatory amino acid transporter 2, GLT1, Glutamate/aspartate transporter II, SLC1A2, Sodium-dependent glutamate/aspartate transporter 2, Solute carrier family 1 member 2 |
| Background | Excitatory amino acid transporter 2 is a ~62 kDa protein. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate. 1. Sutherland, ML. et al. (1995) Gene 162, 271-4. PMID: 7557442 2. Kirschner, MA. et al. (1994) Genomics 24, 218-24. PMID: 7698742 3. Utsunomiya-Tate, N. et al. (1997) FEBS letters 416, 312-6. PMID: 9373176 4. Tanaka, K. et al. (1997) Science (New York, N.Y.) 276, 1699-702. PMID: 9180080 |
| Note | For research use only |
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