Mouse TFAM Recombinant Protein (N-His) (MX990012)

Name: Mouse TFAM Recombinant Protein (N-His)
Brand: abinScience
SKU: MX990012
Price: 211 USD
Availability: InStock

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Catalog No.	MX990012
Description	Recombinant Mouse TFAM Protein, N-His (MX990012) expressed in E. coli, spanning Ser43-Ile200. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P40630
Protein length	Ser43-Ile200
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	20.73 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Mitochondrial transcription factor 1, MtTF1, TCF-6, TCF6, TCF6L2, TFAM, Transcription factor 6, Transcription factor 6-like 2, Transcription factor A, mitochondrial, mtTFA
Background	Transcription factor A, mitochondrial is a ~27 kDa protein. Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. 1. Larsson, NG. et al. (1998) Nature genetics 18, 231-6. PMID: 9500544 2. Kaufman, BA. et al. (2007) Molecular biology of the cell 18, 3225-36. PMID: 17581862
Note	For research use only

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Mouse TFAM Recombinant Protein (N-His).pdf

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Mouse TFAM Recombinant Protein (N-His) (MX990012)

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