Mouse TGFBR3 Recombinant Protein (C-His) (MA790011)

Name: Mouse TGFBR3 Recombinant Protein (C-His)
Brand: abinScience
SKU: MA790011
Price: 298 USD
Availability: InStock

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Catalog No.	MA790011
Description	Recombinant Mouse TGFBR3 Protein, C-His (MA790011) expressed in Mammalian Cells, spanning Met1-Thr785. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	O88393
Protein length	Met1-Thr785
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	88.18 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Betaglycan, TGF-beta receptor type 3, TGF-beta receptor type III, TGFBR3, TGFR-3, Transforming growth factor beta receptor III, Transforming growth factor beta receptor type 3
Background	Transforming growth factor beta receptor type 3 is a ~93 kDa protein. Cell surface receptor that regulates diverse cellular processes including cell proliferation, differentiation, migration, and apoptosis. Initiates BMP, inhibin, and TGF-beta signaling pathways by interacting with different ligands including TGFB1, BMP2, BMP5, BMP7 or GDF5. Alternatively, acts as a cell surface coreceptor for BMP ligands, serving to enhance ligand binding by differentially regulating BMPR1A/ALK3 and BMPR1B/ALK6 receptor trafficking. Promotes epithelial cell adhesion, focal adhesion formation and integrin signaling during epithelial cell spreading on fibronectin. By interacting with the scaffolding protein beta-arrestin2/ARRB2, regulates migration or actin cytoskeleton and promotes the activation of CDC42 as well as the inhibition of NF-kappa-B. 1. Li, Y. et al. (2018) Endocrinology 159, 4077-4091. PMID: 30364975 2. Brûlé, E. et al. (2021) Science advances 7, eabl4391. PMID: 34910520
Note	For research use only

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Mouse TGFBR3 Recombinant Protein (C-His).pdf

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Mouse TGFBR3 Recombinant Protein (C-His) (MA790011)

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