Mouse TYRO3/DTK/SYK Recombinant Protein (C-His) (MC368011)

Name: Mouse TYRO3/DTK/SYK Recombinant Protein (C-His)
Brand: abinScience
SKU: MC368011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MC368011
Description	Recombinant Mouse TYRO3/DTK/SYK Protein, C-His (MC368011) expressed in Mammalian Cells, spanning Ala31-Trp419. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	P55144
Protein length	Ala31-Trp419
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	44.81 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BYK, DTK, EC:2.7.10.1, RSE, SKY, TIF, TYRO3, Tyrosine-protein kinase BYK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase TIF, Tyrosine-protein kinase receptor TYRO3
Background	Tyrosine-protein kinase receptor TYRO3 is a ~96 kDa protein. Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes.
Note	For research use only

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Datasheet

Mouse TYRO3/DTK/SYK Recombinant Protein (C-His).pdf

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Mouse TYRO3/DTK/SYK Recombinant Protein (C-His) (MC368011)

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