Reovirus Outer capsid sigma-1 Recombinant Protein (N-His) (VK138012)

Name: Reovirus Outer capsid sigma-1 Recombinant Protein (N-His)
Brand: abinScience
SKU: VK138012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	VK138012
Description	Recombinant Reovirus Outer capsid protein sigma-1, N-His (VK138012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P04506
Protein length	Val258-Arg470
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Reovirus type 1 (ReV)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Cell attachment protein, Hemagglutinin, Outer capsid protein sigma-1, S1, Sigma1
Background	Outer capsid protein sigma-1 is a ~51 kDa protein. Fiber-like molecule that attaches the virion to the host cell membrane by binding with initial low affinity to sialic acid containing proteins, followed by high-affinity bindingto the entry receptor F11R/JAM-A. Also binds to the ganglioside GM2 as an alternate receptor, this binding is serotype-specific. The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis. 1. Reiss, K. et al. (2012) PLoS pathogens 8, e1003078. PMID: 23236285
Note	For research use only

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Datasheet

Reovirus Outer capsid sigma-1 Recombinant Protein (N-His).pdf

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Reovirus Outer capsid sigma-1 Recombinant Protein (N-His) (VK138012)

Overview

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Datasheet

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