

| Catalog No. | ZV658011 |
|---|---|
| Description |
Recombinant Vicugna pacos IL21 Protein, C-Strep (ZV658011) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | Mammalian cells |
| Accession | XP_006217679.1 |
| Protein length | His25-Ser153 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Vicugna pacos |
| Nature | Recombinant |
| Endotoxin level | <0.1 EU/ug as determined by LAL method. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 18.17 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Interleukin-21 (IL-21,Interleukin-21,IL21,Za11) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. 1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504 2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704 |
| Note | For research use only |
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