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Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO) (HY171026)

Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)
Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)
Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)
Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)
Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)
Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)
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  • Overview

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  • References

  • Datasheet

  • SDS

Overview
Catalog No.HY171026
Description
Abelacimab (HY171026) is a research-grade recombinant antibody targeting Plasma thromboplastin antecedent. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-lambda
Expression system Mammalian cells
Clonality Monoclonal
Target Plasma thromboplastin antecedent, PTA, Coagulation factor XI, F11, FXI
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P03951
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesNVS250519, 2098724-83-3, FXI, FXIa,
Background

Coagulation factor XI (F11) is a ~70 kDa protein. Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Abelacimab.

  • Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)

    Bioactivity

    Detects F11 in indirect ELISAs.

  • Anti-Human Coagulation Factor XI Reference Antibody (Abelacimab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Abelacimab.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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