Anti-Human OX40 Ligand/TNFSF4 Reference Antibody (Amlitelimab, RUO) (HB937026)

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100ug
1mg

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Overview

Catalog No.	HB937026
Description	Amlitelimab (HB937026) is a research-grade recombinant antibody targeting CD252. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG4-Kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	CD252, OX40L, TXGP1, OX40 ligand, Glycoprotein Gp34, TAX transcriptionally-activated glycoprotein 1, TNFSF4, Tumor necrosis factor ligand superfamily member 4
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P23510
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	KY-1005, KY1005, KY1005-2D10, KY-1005-2D10, 2378692-15-8
Background	Tumor necrosis factor ligand superfamily member 4 (CD252/TNFSF4) is a ~21 kDa protein. Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects CD252 in indirect ELISAs.
Bioactivity

Detects Recombinant Human CD252/TNFSF4/OX40L Protein, C-His (Cat No.: HB937021) in indirect ELISA.
Flow CytoMetry

Flow-cytometry using PE anti-human CD252 antibody. HUVEC cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD252 monoclonal antibody (Catalog: HB937026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.