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Anti-CPV VP2 Reference Antibody (Anivovetmab, RUO) (VK689016)

Anti-CPV VP2 Reference Antibody (Anivovetmab, RUO)
Anti-CPV VP2 Reference Antibody (Anivovetmab, RUO)
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Overview
Catalog No.VK689016
Description
Anivovetmab (VK689016) is a research-grade recombinant antibody targeting Capsid protein VP2. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityCanine parvovirus type 2 (CPV2)
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesCanine
IsotypeIgG2, kappa
Expression system Mammalian cells
Clonality Monoclonal
Target Capsid protein VP2
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P61826
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesKIND030, KIND-030, KIND030, 2370896-63-0
Background

Capsid protein VP2 is a ~64 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptor TFRC. This attachment induces virion internalization predominantly through clathrin-endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal(s).

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-CPV VP2 Reference Antibody (Anivovetmab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anivovetmab

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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