

| Catalog No. | VK689016 | ||||
|---|---|---|---|---|---|
| Description |
Anivovetmab (VK689016) is a research-grade recombinant antibody targeting Capsid protein VP2. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Species reactivity | Canine parvovirus type 2 (CPV2) | ||||
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| Host species | Canine | ||||
| Isotype | IgG2, kappa | ||||
| Expression system | Mammalian cells | ||||
| Clonality | Monoclonal | ||||
| Target | Capsid protein VP2 | ||||
| Endotoxin level | Please contact the lab for this information. | ||||
| Purity | >95% purity as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P61826 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Alternate Names | KIND030, KIND-030, KIND030, 2370896-63-0 | ||||
| Background | Capsid protein VP2 is a ~64 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptor TFRC. This attachment induces virion internalization predominantly through clathrin-endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal(s). | ||||
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anivovetmab
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