Anti-Corynephage omega DT/Diphtheria toxin Reference Antibody (DTD4, RUO) (JN967016)

Name: Anti-Corynephage omega DT/Diphtheria toxin Reference Antibody (DTD4, RUO)
Brand: abinScience
SKU: JN967016
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	JN967016
Description	Anti-Corynephage omega DT/Diphtheria toxin Antibody (DTD4) (JN967016) is a research-grade recombinant antibody targeting Diphtheria toxin. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Corynephage omega
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG2-kappa
Clone ID	DTD4
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Diphtheria toxin, DT, NAD(+)--diphthamide ADP-ribosyltransferase, 2.4.2.36, Diphtheria toxin fragment A, Diphtheria toxin fragment B
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P00587
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Diphtheria toxin (DT) is a ~60 kDa protein. Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to elongation factor 2. Fragment A is responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)