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Anti-HIV1 gp41 Reference Antibody (10E8#, RUO) (VK617116)

Anti-HIV1 gp41 Reference Antibody (10E8#, RUO)
Anti-HIV1 gp41 Reference Antibody (10E8#, RUO)
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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  • SDS

Overview
Catalog No.VK617116
Description
Anti-HIV1 gp41 Antibody (10E8#) (VK617116) is a research-grade recombinant antibody targeting Envelope glycoprotein gp160. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2)(HIV-1)
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG
Clone ID10E8#
Expression system Mammalian Cells
Clonality Monoclonal
Target Envelope glycoprotein gp160, Env polyprotein, Surface protein gp120, SU, Glycoprotein 120, gp120, Transmembrane protein gp41, TM, Glycoprotein 41, gp41, env
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P04578
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background

Envelope glycoprotein gp160 (gp41/Glycoprotein 41) is a ~97 kDa protein. Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-HIV1 gp41 Reference Antibody (10E8#, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-HIV1 gp41 Antibody (10E8#)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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