

| Catalog No. | HW342176 |
|---|---|
| Description |
Anti-Human OX40/TNFRSF4 Reference Antibody (MEDI 6469, RUO) (HW342176) is a human monoclonal antibody detecting OX40 Ligand/TNFSF4.
|
| Species reactivity | Human |
| Applications | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Host species | Human |
| Clonality | Monoclonal |
| Isotype | IgG |
| Clone ID | MEDI 6469 |
| Target | ACT35 antigen, CD134, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, TNFRSF4, TXGP1L, Tumor necrosis factor receptor superfamily member 4 |
| Endotoxin level | < 10 EU/mg |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P43489 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | MEDI-6469, MEDI6469, MEDI6469 |
| Background | Tumor necrosis factor receptor superfamily member 4 (CD134/OX40) is a ~29 kDa protein. Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. |
| References | 1. Kim TW, et al. First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors. Clin Cancer Res. 2022 Aug 15;28(16):3452-3463. [HW342176] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-Human CD134/TNFRSF4/OX40 (MEDI 6469).




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