Anti-Human CD83 Reference Antibody (CBT004, RUO) (HX237016)

Name: Anti-Human CD83 Reference Antibody (CBT004, RUO)
Brand: abinScience
SKU: HX237016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HX237016
Description	Anti-Human CD83 (CBT004) (HX237016) is a research-grade recombinant antibody targeting CD83. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	CBT004
Expression system	Mammalian cells
Clonality	Monoclonal
Target	CD83, hCD83, CD83 antigen, B-cell activation protein, Cell surface protein HB15
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q01151
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CBT004
Background	CD83 antigen is a ~23 kDa protein. Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHCII trafficking MARCHF8. Also inhibits MARCHF1 association with MHCII or CD86 to prevent their ubiquitination and subsequent degradation. In addition, acts as an important modulator of protective responses against acute infections. 1. Tze, LE. et al. (2011) The Journal of experimental medicine 208, 149-65. PMID: 21220452
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD83 (CBT004)

References

Datasheet

Anti-Human CD83 Reference Antibody (CBT004, RUO).pdf

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Anti-Human CD83 Reference Antibody (CBT004, RUO) (HX237016)

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