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Anti-Human Cadherin-17 Reference Antibody (PTA001_A4, RUO) (HC546026)

Anti-Human Cadherin-17 Reference Antibody (PTA001_A4, RUO)
Anti-Human Cadherin-17 Reference Antibody (PTA001_A4, RUO)
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Overview
Catalog No.HC546026
Description
Anti-Human CDH17/Cadherin-17 Antibody (PTA001_A4) (HC546026) is a research-grade recombinant antibody targeting CDH17. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG
Clone IDPTA001_A4
Expression system Mammalian cells
Target CDH17, Intestinal peptide-associated transporter HPT-1, LI-cadherin, Liver-intestine cadherin, Cadherin-17
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q12864
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Cadherin-17 (CDH17) is a ~92 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Cadherin-17 Reference Antibody (PTA001_A4, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CDH17/Cadherin-17 Antibody (PTA001_A4)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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