Anti-Human DLL3 Reference Antibody (AMG 119, RUO) (HP628036)

Name: Anti-Human DLL3 Reference Antibody (AMG 119, RUO)
Brand: abinScience
SKU: HP628036
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HP628036
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	AMG 119
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Drosophila Delta homolog 3, Delta3, Delta-like protein 3, DLL3
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9NYJ7
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	AMG-119, AMG119, AMG119
Background	Delta-like protein 3 (DLL3) is a ~64 kDa protein. Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
References	1. Zhou D, et al. Clinical Pharmacology Profile of AMG 119, the First Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting Delta-Like Ligand 3 (DLL3), in Patients with Relapsed/Refractory Small Cell Lung Cancer (SCLC). J Clin Pharmacol. 2024 Mar;64(3):362-370. [HP628036]
Note	For research use only. Not suitable for clinical or therapeutic use.