Anti-Human EDNRB/Endothelin R Type B Reference Antibody (DEDN6526A, RUO) (HB173016)

Name: Anti-Human EDNRB/Endothelin R Type B Reference Antibody (DEDN6526A, RUO)
Brand: abinScience
SKU: HB173016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HB173016
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	DEDN6526A
Expression system	Mammalian cells
Target	Endothelin receptor type B, EDNRB, ETRB, ET-BR, Endothelin receptor non-selective type, ET-B
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P24530
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	DEDN6526A, DEDN6526A, DEDN-6526A
Background	Endothelin receptor type B (EDNRB/ETRB) is a ~49 kDa protein. Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
References	1. Sandhu S, et al. Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma. Invest New Drugs. 2020 Jun;38(3):844-854. [HB173016]
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human EDNRB/ETRB Antibody (DEDN6526A)

References

Datasheet

Anti-Human EDNRB/Endothelin R Type B Reference Antibody (DEDN6526A, RUO).pdf

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Anti-Human EDNRB/Endothelin R Type B Reference Antibody (DEDN6526A, RUO) (HB173016)

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