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Anti-Human IL38/IL1F10 Reference Antibody (IMM-ONC-01) (HV323016)

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Anti-Human IL38/IL1F10 Reference Antibody (IMM-ONC-01)

Anti-Human IL38/IL1F10 Reference Antibody (IMM-ONC-01)

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Spec:

100ug
1mg

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Datasheet

Overview

Catalog No.	HV323016
Description	Anti-Human IL38/IL1F10 Antibody (IMM-ONC-01) (HV323016) is a research-grade recombinant antibody targeting Interleukin-1 family member 10. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1
Clone ID	IMM-ONC-01
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Interleukin-1 family member 10, IL-1F10, Family of interleukin 1-theta, FIL1 theta, Interleukin-1 HY2, IL-1HY2, Interleukin-1 theta, IL-1 theta, Interleukin-38, IL-38, IL1F10, FIL1T, IL1HY2, IL38, FKSG75, UNQ6119/PRO20041
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q8WWZ1
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background	Interleukin-1 family member 10 (IL38/IL1F10) is a ~16 kDa protein. Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human IL38/IL1F10 Antibody (IMM-ONC-01)

References

Datasheet

Anti-Human IL38/IL1F10 Reference Antibody (IMM-ONC-01).pdf

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Anti-Human IL38/IL1F10 Reference Antibody (IMM-ONC-01)