Anti-Human PTH Reference Antibody (ABX-PTH, RUO) (HF921016)

Name: Anti-Human PTH Reference Antibody (ABX-PTH, RUO)
Brand: abinScience
SKU: HF921016
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	HF921016
Description	Anti-Human PTH (ABX-PTH) (HF921016) is a research-grade recombinant antibody targeting Parathyroid hormone. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	ABX-PTH
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Parathyroid hormone, Parathormone, PTH, Parathyrin
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01270
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ABX-PTH, ABXPTH, ABXPTH
Background	Parathyroid hormone (PTH) is a ~12 kDa protein. Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. 1. Shimizu, N. et al. (2001) The Journal of biological chemistry 276, 49003-12. PMID: 11604398 2. Kobayashi, K. et al. (2022) Molecular cell 82, 3468-3483.e5. PMID: 35932760 3. Pioszak, AA. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5034-9. PMID: 18375760 4. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856
Note	For research use only. Not suitable for clinical or therapeutic use.