

| Catalog No. | HP075016 |
|---|---|
| Description |
Anti-Human SLC2A8/GLUT8 (VB1-050) (HP075016) is a research-grade recombinant antibody targeting Glucose transporter type X1. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Host species | Human |
| Clonality | Monoclonal |
| Isotype | IgG |
| Clone ID | VB1-050 |
| Expression system | Mammalian cells |
| Nature | Recombinant |
| Target | Glucose transporter type X1, GLUT-8, Glucose transporter type 8, GLUTX1, SLC2A8, Solute carrier family 2, facilitated glucose transporter member 8, GLUT8 |
| Endotoxin level | < 10 EU/mg as determined by LAL method. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q9NY64 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | VB1-050, VB1050, VB1050 |
| Background | Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8GLUT8) is a ~50 kDa protein. Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate. 1. Mayer, AL. et al. (2016) Scientific reports 6, 38586. PMID: 27922102 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-Human SLC2A8GLUT8 (VB1-050)
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