Anti-Human TSLPR Reference Antibody (RG-7258, RUO) (HP521026)

Name: Anti-Human TSLPR Reference Antibody (RG-7258, RUO)
Brand: abinScience
SKU: HP521026
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HP521026
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	RG-7258
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR, Thymic stromal lymphopoietin protein receptor, TSLP receptor, CRLF2, CRL2, ILXR, TSLPR
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9HC73
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	RG-7258, RG7258, RG7258
Background	Cytokine receptor-like factor 2 (TSLPR/CRLF2) is a ~42 kDa protein. Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system.
References	1. Fuentes M E, et al. Anti-TSLPR antibody RG7258 blocks dendritic cell activation, mast cell cytokine release and reduces Th2 inflammation in a non-human primate model of allergic lung inflammation[M]//B32. ALLERGIC INFLAMMATION: MECHANISMS. American Thoracic Society, 2011: A2767-A2767. [HP521026]
Note	For research use only. Not suitable for clinical or therapeutic use.