Anti-Human VSIG4 Reference Antibody (VTX-1218, RUO) (HP545026)

Name: Anti-Human VSIG4 Reference Antibody (VTX-1218, RUO)
Brand: abinScience
SKU: HP545026
Price: 176 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HP545026
Description	Anti-VSIG4/CRIg Antibody (VTX-1218) (HP545026) is a research-grade recombinant antibody targeting Protein Z39Ig. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, kappa
Clone ID	VTX-1218
Expression system	Mammalian cells
Clonality	Monoclonal
Tested applications	FCM
Target	Protein Z39Ig, CRIg, V-set and immunoglobulin domain-containing protein 4, VSIG4, Z39IG
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9Y279
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	V-set and immunoglobulin domain-containing protein 4 (VSIG4/CRIg) is a ~43 kDa protein. Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) Human IgG1 (E356D/M358L), kappa Recombinant Isotype Control Antibody (HyHEL-10) (HV080013) Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

Images

Bioactivity

Detects VSIG4 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Anti-VSIG4/CRIg Antibody (VTX-1218).
Flow cytometry

Flow-cytometry APC using anti-human VSIG4 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human VSIG4 monoclonal antibody (Catalog HP545026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry PE using anti-human VSIG4 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an PE anti-human VSIG4 monoclonal antibody (Catalog HP545026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry FITC using anti-human VSIG4 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an FITC anti-human VSIG4 monoclonal antibody (Catalog HP545026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.