Anti-Human CEACAM-5/CD66e Reference Antibody (Arcitumomab, RUO) (HY546013)

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY546013

Description

Arcitumomab (HY546013) is a research-grade recombinant antibody targeting CD66. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Species reactivity

Human

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Host species

Mouse

Isotype

IgG2a

Expression system

Mammalian Cells

Clonality

Monoclonal

Target

Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen

Endotoxin level

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06731

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

CEA-Scan, IMMU-4, 154361-48-5

Background

Cell adhesion molecule CEACAM5 (CD66e) is a ~76 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.

1. Taheri, M. et al. (2000) The Journal of biological chemistry 275, 26935-43. PMID: 10864933

2. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050

3. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

Detects Human CD66e/CEA/CEACAM5 in direct ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Arcitumomab.

References

Datasheet

Anti-Human CEACAM-5/CD66e Reference Antibody (Arcitumomab, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CEACAM-5/CD66e Reference Antibody (Arcitumomab, RUO) (HY546013)

Overview

Images

References

Datasheet

SDS

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