Research Grade Batiraxcept (HC347036)

Name: Research Grade Batiraxcept
Brand: abinScience
SKU: HC347036
Price: 320 USD
Availability: InStock

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Overview

Catalog No.	HC347036
Description	Batiraxcept (HC347036) is a research-grade recombinant antibody targeting AXLLG. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Functional assay, Research in vivo
Isotype	Fusion - [AXL (AXL receptor tyrosine kinase, ARK, JTK11, Tyro7, UFO)]2 - IGHG1 Fc (Fragment constant)
Expression system	Mammalian cells
Target	AXLLG, Growth arrest-specific protein 6, AXL receptor tyrosine kinase ligand, GAS6, GAS-6
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q14393
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	AVB-500, AVB-S6-500, Aravive-S6, MYD1Fc, Ruga-S6, 2268717-61-7
Background	Growth arrest-specific protein 6 (GAS6) is a ~74 kDa protein. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Note	For research use only. Not suitable for clinical or therapeutic use.