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Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO) (HV212016)

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Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)

Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)

Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)

Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)

Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)

Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)

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Spec:

100ug
1mg

Number:

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	HV212016
Description	Belimumab (HV212016) is a research-grade recombinant antibody targeting CD257. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-lambda
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	BAFF, ZTNF4, BLYS, Tumor necrosis factor ligand superfamily member 13B, Dendritic cell-derived TNF-like molecule, TALL-1, TNF- and APOL-related leukocyte expressed ligand 1, BLyS, B lymphocyte stimulator, TNFSF13B, CD257, TNFSF20, TALL1, B-cell-activating factor
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9Y275
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	LymphoStat-B, hBlySmAb-1.1, 356547-88-1
Background	Tumor necrosis factor ligand superfamily member 13B (CD257/BAFF) is a ~31 kDa protein. Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

SEC-HPLC detection for Research Grade Belimumab.
SDS-PAGE

SDS-PAGE for Research Grade Belimumab
Western blot

Western blot analysis was performed using anti-CD257/BAFF/TNFSF13B monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD257/BAFF/TNFSF13B (Catalog No: HV212011)
Lane 2: negative control

References

Datasheet

Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO).pdf

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Formula

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Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)